Trisha's first release was Mounam Pesiyadhey though it was Lesa Lesa which she had signed first. In Mounam Pesiyadhey she paired with Surya and the movie shaped out well. Her second release was Manasellam in which she paired with Srikanth and the movie was also a good hit. After her second release she got several offers and her movies which hit the box office were Ghilli opposite Vijay, Saami opposite Vikram, and Unakku Iruvathu Enakku Pathinettu opposite Tharun, ManiRathnam's Ayutha Ezhuthu, Thirupaachi opposite Vijay and Ji opposite Ajith. She has also done several movies in Telugu. The Telugu movie Varsham in which she paired with Prabahs was a great hit. Nuvvostanante Ne Vaddantana was also another hit where she paired with Siddartha.

Her new releases are Abhiyum Naanum, Chennaiyil Oru Mazhaikalam opposite four new faces, Bezawada Bujji opposite Ravi Teja, and Bujjigadu opposite Prabhas.